ring-opening strain of hexamethylcyclotrisiloxane, like neighbouring dinitrogen Philippines, is a bidentate ligand, it can capture enzyme and other biological molecules through the coordination reaction of metal ions, or like cyanide, although not win, but its side closed for reaction, Destroy its structure and function. EDTA, for example, is commonly used to detoxify and remove excess metal ions from the body, but in excess it is enough on its own to damage enzymes that prevent DNA mutations and cause cancer.
This is the main toxicity. Second, like benzene, it may have secondary degradation products that contain bonds such as epoxy bonds, which may be inactivated by alkylation with DNA bases or protein amino groups.
Toxoxanthin, by the way, is A base substitute, and it causes cancer because it doesn't have a particularly fixed pairing with the known bases, so this time it's A, next time it's C or something like that, which distorts the information in DNA replication.
ring-opening strain of hexamethylcyclotrisiloxane https://www.clentpharma.com/Hexamethylcyclotrisiloxane.html